Could a glass of wine at dinner time be the next major arthritis breakthrough?

Could a glass of wine at dinner time be the next major arthritis breakthrough?

Possibly..according to a recent Swedish studyA diet of 10% ethanol had a protective effect on mice that would otherwise have developed collagen-induced arthritis (CIA), Sw

Could a glass of wine at dinner time be the next major arthritis breakthrough?

Possibly..according to a recent Swedish studyA diet of 10% ethanol had a protective effect on mice that would otherwise have developed collagen-induced arthritis (CIA), Swedish researchers report in Proceedings of the National Academy of SciencesCIA is often used as an animal model of human rheumatoid arthritis (RA.)

Andrej Tarkowski, MD, the senior author and a faculty member in the department of rheumatology and inflammation research, Goteborg University, in Sweden, stated that the primary finding was that, in male mice, long term consumption of 10% ethanol delayed the onset and progression of CIA.

The underlying mechanism appears to be a reduction in inflammation due to decreased NF-kB activation (a primary inflammatory pathway) caused by upregulation- or increased production -of testosterone secretion.

The research team fused a CIA model in mice by immunizing male DBA/1 mice with collagen type II (CII)To determine whether drinking ethanol has any impact on the development of CIA, the mice were provided with either 10% ethanol or water alone to drinkMice were sacrificed after 5 to 6 weeksAll four paws from DBA/1 mice were sectioned, stained, and examined for inflammation of the joint including damage to the joint lining and erosion of bone and cartilage

ish researchers report in Proceedings of the National Academy of SciencesCIA is often used as an animal model of human rheumatoid arthritis (RA.)

Andrej Tarkowski, MD, the senior author and a faculty member in the department of rheumatology and inflammation research, Goteborg University, in Sweden, stated that the primary finding was that, in male mice, long term consumption of 10% ethanol delayed the onset and progression of CIA.

The underlying mechanism appears to be a reduction in inflammation due to decreased NF-kB activation (a primary inflammatory pathway) caused by upregulation- or increased production -of testosterone secretion.

The research team fused a CIA model in mice by immunizing male DBA/1 mice with collagen type II (CII)To determine whether drinking ethanol has any impact on the development of CIA, the mice were provided with either 10% ethanol or water alone to drinkMice were sacrificed after 5 to 6 weeksAll four paws from DBA/1 mice were sectioned, stained, and examined for inflammation of the joint including damage to the joint lining and erosion of bone and cartilage

Andrej Tarkowski, MD, the senior author and a faculty member in the department of rheumatology and inflammation research, Goteborg University, in Sweden, stated that the primary finding was that, in male mice, long term consumption of 10% ethanol delayed the onset and progression of CIA.

The underlying mechanism appears to be a reduction in inflammation due to decreased NF-kB activation (a primary inflammatory pathway) caused by upregulation- or increased production -of testosterone secretion.

The research team fused a CIA model in mice by immunizing male DBA/1 mice with collagen type II (CII)To determine whether drinking ethanol has any impact on the development of CIA, the mice were provided with either 10% ethanol or water alone to drinkMice were sacrificed after 5 to 6 weeksAll four paws from DBA/1 mice were sectioned, stained, and examined for inflammation of the joint including damage to the joint lining and erosion of bone and cartilage